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This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

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For people with sickle cell anemia: This drug may cause a common painful complication of sickle cell anemia called vaso-occlusive crisis. If you have sickle cell anemia, ask your doctor whether this drug is safe for you.

For PAH: Sildenafil works by relaxing the muscles and opening up the blood vessels in your lungs. This decreases the blood pressure in your lungs. Sildenafil slows down the progression of your illness. It also makes you more able to exercise.

The most effective ED pill for you will vary depending on your needs, health, and other medications you may already be taking.

Talk with your doctor if you’re pregnant or planning to become pregnant. It appears unlikely that this drug will harm a pregnancy. However, this drug should only be used during pregnancy if clearly needed.

Sildenafil oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level.

For children: This drug isn’t recommended in children younger than 18 years. In one study, children with PAH who took this drug had an increased chance for death.

The kidneys, liver, or heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk for side effects.

Use in children warning: Children generally should not take sildenafil; however, there are instances where the drug is considered the best treatment option. Talk with website your child’s doctor to better understand the benefits and risks associated with this treatment option.

For seniors: The kidneys, liver, or heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk for side effects.

For people with problems with the shape of their penis: If you have a problem with the shape of your penis, such as Peyronie’s disease, this drug raises your risk for having an erection that lasts more than 4 hours.

Tadalafil is the generic name for the erectile dysfunction drug Cialis. There are two versions of the drug: